Night serum supporting the regeneration of acne-prone skin Anti-Acne Orphica Clinic 50 ml

hydrolipid balance and renewal of acne-prone skin
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  • care and support for acne-prone skin
  • reduces imperfections and sebum
  • support in evening out skin tone
  • 50 ml
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Orphica Clinic Anti-Acne Night Serum: targeted regeneration for problematic skin


Night serum ORPHICA Clinic Anti-Acne features an advanced formula based on RetiClear Complex™, combining the effects of retinol and squalane to support nighttime skin regeneration. This product is designed for skin prone to imperfections that needs effective care while maintaining the hydrolipid balance. Thanks to its concentrated active ingredients, the serum supports the cell renewal process, helps reduce excess sebum production, and improves overall skin condition. Its light, emulsion texture absorbs well and works during the night when the skin regenerates most intensively.

Advanced action and repair while you sleep

  • Squalane 2%: helps moisturize, smooth the skin, and protect the hydrolipid barrier. Supports defense against external factors and leaves the skin soft and smooth.
  • Hyaluronic acid 1%: deeply hydrates, binds water in the epidermis to maintain optimal moisture levels, and protects the skin from transepidermal water loss (TEWL). Strengthens the protective barrier and improves skin elasticity.
  • Retinol 0.3%: accelerates the natural skin renewal process, stimulates collagen and elastin synthesis, reduces the visibility of acne scars and post-inflammatory hyperpigmentation. Normalizes keratinization, reducing the tendency to develop blackheads and microinflammatory lesions. Regular use improves skin texture and density.
  • Phospholipids: support the restoration of the hydrolipid barrier and soothe irritation. They have regenerative and calming properties.
The serum formula combines ingredients with proven skincare benefits that work synergistically during nighttime skin regeneration. Retinol supports cell renewal, helping to smooth the skin and improve its texture. Squalane acts as an emollient, supporting skin repair and protecting the hydrolipid barrier from moisture loss. Hyaluronic acid intensely moisturizes, binding water in the epidermis and supporting elasticity and regeneration. Phospholipids further help restore the skin’s protective barrier and soothe irritation. Together, they create a thoughtful composition that supports the skin during nighttime regeneration, especially for combination, oily, and problematic skin struggling with imperfections, excess sebum, uneven texture, and signs of disrupted skin balance.

  • supports cell renewal and smooths the skin
  • helps reduce excess sebum and imperfections
  • supports evening out skin tone
Aqua, Coco-Caprylate/Caprate, C13-15 Alkane, Propanediol, Glycerin, Caprylic/Capric Triglyceride, Squalane, Glyceryl Stearate Citrate, Lysolecithin, Sclerotium Gum, Phospholipids, Sodium Hyaluronate, Retinol, Cetyl Alcohol, Pullulan, Xanthan Gum, Glycine Soja Oil, Sodium Phytate, Phenoxyethanol, Ethylhexylglycerin, Tocopherol, Silica, Beta-Sitosterol, Squalene.

Apply to cleansed facial skin, avoiding the eye area. Use at night depending on your skin's condition and needs, and wait about 30-40 minutes before applying the next dermocosmetic in your routine. During the day, make sure to protect your skin from UV radiation.

Introducing pure retinol into your skincare routine requires careful adherence to the schedule to minimize the risk of irritation and temporary damage to the skin’s moisture barrier. Whether it’s your first treatment or resuming it, start with low concentrations, preferably 0.3%. Begin by applying the serum every 4th evening for the first 3 weeks. After that, you can increase the frequency to every 3rd evening.
Week 1–3: Apply every 4th evening.
Week 4–5: Increase frequency to every 3rd evening (provided there are no signs of overreaction).
Week 6–7: Intensify to every 2nd evening.

Can the serum be used daily?
The serum can be used at night depending on your skin's needs. For sensitive skin, it is recommended to introduce the product gradually.
Is the retinol in the formula safe?
Yes, the retinol concentration has been carefully selected to support skin renewal while maintaining comfort. Please use the product as directed.
Is the serum suitable for acne-prone skin?
Yes, the formula is designed for problematic skin, including acne-prone skin – it helps reduce imperfections and regulate sebum.
Do I need to use SPF while using this product?
Yes, when using products with retinol, daily sun protection with at least SPF50 during the day is recommended.
Does the serum moisturize the skin?
Yes, thanks to squalane and hyaluronic acid, the serum supports hydration and helps maintain the skin’s moisture balance.
Can the product cause irritation?
At the beginning of use, retinol may cause slight irritation. It is advised to monitor your skin and adjust the application frequency according to its needs.

Squalane: 2%
Sodium Hyaluronate: 1%
Retinol: 0.3%
Phospholipids

Orphica Clinic is a dermocosmetic brand created for skin in need of real solutions. Each formula is based on active ingredients with proven efficacy – purposefully selected in optimal concentrations to target specific skin concerns. We create effective skincare regimes tailored to the actual needs of the skin.

Abriga Limited Liability Company

Centre Atlas, CS 70013
24 Avenue du Prado
13286 Marseille Cedex 06, France

Person responsible in the EU:
Abriga Sp. z o.o.
ul. Staromiejska 8/12
26-600 Radom, PL,
kontakt@nutridome.pl
phone: +48 22 266 10 01